Viruses, endoplasmic reticulum stress, and interferon responses
نویسندگان
چکیده
منابع مشابه
Integrated endoplasmic reticulum stress responses in cancer.
The endoplasmic reticulum (ER) has emerged as a major site of cellular homeostasis regulation, particularly in the unfolded protein response, which is being found to play a major role in cancer and many other diseases. Here, we address ER-mediated signaling and regulations in the context of environmental challenges in cancer, such as hypoxia, angiogenesis, and chemotherapeutic resistance, and w...
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The defects in storage proteins secretion in the endosperm of transgenic rice seeds often leads to endoplasmic reticulum (ER) stress, which produces floury and shrunken seeds, but the mechanism of this response remains unclear. We used an iTRAQ-based proteomics analysis of ER-stressed rice seeds due to the endosperm-specific suppression of OsSar1 to identify changes in the protein levels in res...
متن کاملShort communication Vanadate inhibits endoplasmic reticulum stress responses
The disruption of endoplasmic reticulum function leads to an accumulation of unfolded proteins, which results in endoplasmic reticulum stress. In the present study, we investigated the effect of vanadate on such stress. Endoplasmic reticulum stress increased glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) expressions in glial cell cultures. We f...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2006
ISSN: 1350-9047,1476-5403
DOI: 10.1038/sj.cdd.4401833